International Journal of Research in Pharmacy and Allied Science

ISSN: 2583-6544   |  Issues per year: Monthly  |   Indexed In: Google Scholar, CORE, ScienceOpen, Researchgate

ISSN:2583-6544

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FT-IR and UV-Vis Spectroscopic studies of Cd(II), Hg(II) and Zn(II) metal complexes of 2-methoxy-2'-hydroxychalcone

Author(s): Adebayo T. Bale*1, Wahab A. Osunniran2, Mohammed H. Sadiya3, Fausat O. Adebona4

Email(s): 1adebayo.bale@kwasu.edu.ng

Address:

    Kwara State University, Nigeria

Published In:   Volume - 4,      Issue - 4,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4411  

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ABSTRACT:
Chalcones are naturally occurring and synthetically produced compounds belonging to the flavonoid family exhibiting numerous biological properties like anticancer, antidiabetic, antimicrobial and antioxidant activities. In this study, chalcone synthesis was accomplished using conventional solution method (Claisen-Schmidt condensation reaction), while the metal complexes were prepared via mechanochemistry. The reaction between 2-methoxybenzaldehyde and 2-hydroxyacetophenone yielded a yellow chalcone. The synthesis of metal complexes involved reacting the ligand with mercury(II), Zinc(II) and Cadmium(II) chlorides in a 2:1 millimolar ratio, resulting in the formation of brown, light yellow and light grey coloured complexes respectively. The chalcone and the metal complexes were analyzed using various techniques such as melting point, solubility test, FT-IR and UV-Vis spectroscopy. The chalcone melted at 117 oC, whereas Hg(II), Zn(II) and Cd(II) showed higher melting points at 196 oC, 190 oC and 175 oC respectively indicating thermal stability. The chalcone and their metal complexes were found to be soluble, partially soluble and insoluble in polar solvents. The FT-IR results indicated the formation of carbonyl (C=O, 1615-1639 cm-1) and aromatic C=C (1552-1634 cm-1) diagnostic absorption bands. The spectra of the metal complexes showed M-O band in between 469-603 cm-1.

Keywords:

Cite this article:
Adebayo T. Bale, Wahab A. Osunniran, Mohammed H. Sadiya, Faosat O. Adebona. FT-IR and UV-Vis Spectroscopic studies of Cd(II), Hg(II) and Zn(II) metal complexes of 2-methoxy-2'-hydroxychalcone.IJRPAS, April 2025; 4 (4): 103-112.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4411


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