International Journal of Research in Pharmacy and Allied Science

ISSN: 2583-6544   |  Issues per year: Monthly  |   Indexed In: Google Scholar, CORE, ScienceOpen, Researchgate

ISSN:2583-6544

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Gastroretentive Drug Delivery System

Author(s): Bhakti Narayan Patil *1, Momin Abrarul Haque2, Manali Maheshwar Patil.3, Mayur Suresh Reddy4, Ankita Bhagoji Dupare.5

Email(s): 1bhaktinpatil0802@gmail.com

Address:

    M. S. College of Pharmacy, Gaurapur-Kudus Rd, Dist. Palghar, Maharashtra, India.

Published In:   Volume - 2,      Issue - 5,     Year - 2023

DOI: Not Available

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ABSTRACT:
The most convenient way to deliver drugs is through the oral route because it's easy for patients to take, reliable, and allows for different types of medicines to be given easily. In this review physiology of the stomach along with its motility pattern usually called migrating motor complex (MMC) is discussed. The reason for writing this review about gastroprotective drug delivery systems is to gather recent information about methods that help medicines stay in the stomach for a longer time when taken orally. This is important for controlled release drug delivery to specific sites in the body. To understand why drugs might not stay in the stomach, study the factors that affect gastric retention. Then, discussed various approaches that have been developed to make drugs stay in the stomach. These include methods like making the drug sink in the stomach, float on top, stick to the stomach lining, expand, unfold, use special porous materials, or even use magnets, then advantages, limitations, suitable drug candidates, and factors affecting GRDDS are discussed.

Keywords:

Cite this article:
Bhakti Narayan Patil *, Momin Abrarul Haque, Manali Maheshwar Patil., Mayur Suresh Reddy, Ankita Bhagoji Dupare. Gastroretentive Drug Delivery System. IJRPAS, Sep-Oct 2023; 2(5): 71-86.


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