ABSTRACT:
Mouth-dissolving films (MDFs) have emerged as a promising drug delivery system, revolutionizing the pharmaceutical industry by addressing challenges related to conventional dosage forms. This paper explores recent innovations in MDFs, focusing on enhancing drug delivery efficacy and improving patient compliance. The review discusses various formulation techniques, such as solvent casting and hot-melt extrusion, which contribute to the development of MDFs with improved mechanical properties and drug release profiles. Furthermore, the impact of different polymers, plasticizers, and disintegrating agents on the performance of MDFs is examined. Special attention is given to the incorporation of novel drug delivery technologies, including nanostructured systems and mucoadhesive polymers, to enhance the bioavailability of drugs through the oral mucosa. Additionally, the paper highlights the influence of taste-masking strategies on patient acceptance and compliance. Overall, this comprehensive review provides insights into the current state of innovations in MDFs, shedding light on their potential to overcome challenges associated with traditional drug delivery systems.
Cite this article:
Mr. Faizan Ahmed, Mujahid Ahmed Haroon Rasheed, Pathan Junaid Moinuddin, Obaidurraheman Mohammed Saleem.The Review on Innovations in Mouth Dissolving Films: Enhancing Drug Delivery and Patient Compliance.IJRPAS, March-April 2024; 3(2):58-71
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