ABSTRACT:
Investigations were conducted on the polyphenolic content, in vitro antioxidant activity, and antiulcer properties of the methanolic extract of Millingtonia hortensis Linn flowers MEMHF. Reducing power, hydroxyl radical activity, and superoxide anion scavenging, while the antiulcer activity was evaluated using rat pylorus ligation. As the quantity of extract rose (5-100μg/ml), the antioxidant activity also increased. The total flavonoid and phenol concentrations of MEMHF were determined to be 31.69 mg/ml GAE and 163.73 mg/ml QE per 1000 mg of extract, respectively. Pretreatment with MEMHF at doses of 250 and 500 mg/kg resulted in a substantial reduction in stomach volume, total acidity, free acidity, and ulcer index. Additionally, it raised pH in comparison to the control group, indicating antiulcer action. At the very least, some of the reported antioxidant and antiulcer action may be attributable to the presence of phenols and flavonoids.
Cite this article:
Rashmi Rajeghorpade, Varsha Shende, Vinod Pawar, Sohan Patel, Satyajit Sahoo. Screening of In-Vitro Antioxidant and Antiulcer Activity of Millingtonia hortensis Linn Flowers. IJRPAS, 2024; 3(4): 39-50.
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