Turmeric-Based Mouth Dissolving Film for Ulcer Treatment

Author(s): Mr. Pawar Jaydeep*¹, ², Mr. Yalse Manoj³, Sonwane Sumit⁴

Email(s): ¹jaydeeppawar241@gmail.com

Address:

Mahatma Gandhi Vidyamandir Samajshri Prashandada Hiray College of Pharmacy, Malegaon- 423203, Maharashtra

Published In: Volume - 4, Issue - 2, Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4211

View HTML

View PDF

Please allow Pop-Up for this website to view PDF file.

ABSTRACT:
This study explores the formulation and evaluation of a turmeric-based mouth dissolving film (MDF) designed for ulcer treatment. Turmeric, known for its active compound curcumin, possesses anti-inflammatory and antimicrobial properties that can aid in ulcer healing. The MDF provides a convenient and effective mode of drug delivery, ensuring rapid disintegration and absorption. The study involves formulation, characterization, and in vitro evaluation of the film, assessing parameters like tensile strength, disintegration time, and drug release profile. Results indicate enhanced curcumin bioavailability and improved therapeutic efficacy, making it a promising alternative for ulcer management. Additionally, the study investigates the stability and storage conditions of the MDFs to determine their shelf life and efficacy over time.

Keywords:

Cite this article:
Mr. Pawar Jaydeep, Mr. Yalse Manoj, Sonwane Sumit.Turmeric-Based Mouth Dissolving Film for Ulcer Treatment. IJRPAS, Feb 2025; 4 (2): 115-118.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4211

Sharma A, et al. "Curcumin and Its Medicinal Properties: A Review." Int J Pharm Sci. 2022; 14(3): 123-130.
Patel K, et al. "Mouth Dissolving Films: An Innovative Approach in Drug Delivery." J Pharm Res. 2021; 13(2): 89-95.
World Health Organization. "Traditional Medicine and Modern Healthcare." WHO Guidelines, 2020.
Gupta R, et al. "Development of Fast Dissolving Films for Drug Delivery." Drug Dev Ind Pharm. 2019; 45(4): 567-574.
Bose S, et al. "Stability Analysis of Oral Dissolving Films: A Review." J Adv Pharm Sci. 2020; 16(2): 78-85.
Chattopadhyay I, et al. "Turmeric and Curcumin: Biological Actions and Medicinal Applications." Current Science. 2004; 87(1): 44-50.
Rowe RC, Sheskey PJ, Quinn ME. "Handbook of Pharmaceutical Excipients." 6th ed. London: Pharmaceutical Press; 2009.
Saini R, et al. "Oral Mucosal Drug Delivery: An Overview." Int J Pharm Sci Res. 2016; 7(10): 3913-3926.
WebMD. "Turmeric: Uses, Side Effects, and More." [Internet]. [cited 2024 Feb 21]. Available from: https://www.webmd.com/vitamins/ai/ingredientmono-662/turmeric
National Center for Biotechnology Information. "Curcumin: A Review of Its Effects on Human Health." [Internet]. [cited 2024 Feb 21]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/