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Author(s): Sanika Lawhale*1, Jayashri Dalal2, Vaidehi Patil3, Shweta Dehare4, Tej Sidam5

Email(s): 1aasyas123@gmail.com

Address:

    Agnihotri Institute of Pharmacy, Wardha: 442001, Maharashtra, India.

Published In:   Volume - 4,      Issue - 3,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4319  

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ABSTRACT:
Herbal formulations have gained significant attention in dermatological applications due to their efficacy and minimal side effects. Kalmegh (Andrographis paniculata), known for its antimicrobial, anti-inflammatory, and antioxidant properties, is widely used in traditional medicine. This study focuses on the formulation and evaluation of a herbal cream containing Kalmegh extract to assess its physicochemical properties and therapeutic potential.

Cite this article:
Sanika Lawhale, Jayashri Dalal, Vaidehi Patil, Shweta Dehare, Tej Sidam. Formulation and Evaluation of Andrographis paniculata nees (Kalmegh Powder). IJRPAS, March 2025; 4 (3): 141-145.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4319


1.        Karnik A, Desai S, Desai D, Patel P. Formulation development and evaluation of Andrographis paniculata cream. Int J Biol Pharm Allied Sci. 2024;13(7):3134-43. Available from: https://ijbpas.com/pdf/2024/July/MS_IJBPAS_2024_7773.pdf

2.        Aney JS, Nida M. Formulation and evaluation of herbal topical gel containing leaves extract of Andrographis paniculataJ Drug Deliv Ther. 2020;10(1):204-9.

3.        Kshirsagar SJ, Bhalerao SS, Desai VS, Desai SR. Design, formulation and evaluation of oxymel containing Andrographis paniculata extract. Int J Pharm Investig. 2020;10(4):456-60.

4.        Jayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. Available from: https://doi.org/10.1155/2013/846740

5.        Lim JC, Chan TK, Ng DS, Sagineedu SR, Stanslas J, Wong WS. Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer. Clin Exp Pharmacol Physiol. 2012;39(3):300-10. Available from: https://doi.org/10.1111/j.1440-1681.2011.05623.x

6.        Okhuarobo A, Ehigiator O, Falodun J, Falodun A. Evaluation of the medicinal uses and phytochemistry of Andrographis paniculata (Burm. f.) Nees. Indian J Med Res. 2014;139(1):118-27. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032030/

7.        Panraksa P, Ramphan S, Khongwichit S, Smith DR. Activity of andrographolide against dengue virus. Antiviral Res. 2017;139:69-77. Available from: https://doi.org/10.1016/j.antiviral.2016.12.012

8.        Gupta S, Mishra KP, Ganju L. Broad-spectrum antiviral properties of andrographolide. Arch Virol. 2021;166(2):575-85. Available from: https://doi.org/10.1007/s00705-020-04842-y

9.        Abu-Ghefreh AA, Canatan H, Ezeamuzie CI. In vitro and in vivo anti-inflammatory effects of andrographolide. Int Immunopharmacol. 2009;9(3):313-8. Available from: https://doi.org/10.1016/j.intimp.2008.12.008

10.    Tang T, Targan SR, Karp LC. Andrographolide’s mechanism of immunomodulation and anti-inflammatory effects. J Ethnopharmacol. 2018;223:108-17. Available from: https://doi.org/10.1016/j.jep.2018.04.032

11.    Mishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): A review on its pharmacological aspects and clinical applications. J Ethnopharmacol. 2007;114(3):501-15. Available from: https://doi.org/10.1016/j.jep.2007.08.017

12.    Roy SD, Rathod R, Mahadik KR. Development and evaluation of a topical formulation containing Andrographis paniculata extract. Int J Pharm Sci Res. 2019;10(5):2152-60. Available from: https://doi.org/10.13040/IJPSR.0975-8232

13.    Subramanian R, Asmawi MZ, Sadikun A. In vitro antioxidant activity of various fractions of Andrographis paniculata leaves. J Med Plants Res. 2008;2(10):390-5. Available from: https://academicjournals.org/journal/JMPR/article-abstract/

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