Author(s):
Dr. Sundhararajan R1, A. Dhanalakshmi*2, Latha. S3, Lokesh. S4, Manibharathi. K5, Megala. S6, Mohamed Adhil. A7
Email(s):
1dhanaanbu26@gmail.com
Address:
Mohammad Sathak A.J. College of Pharmacy, Chennai, Tamil Nadu.
Published In:
Volume - 4,
Issue - 3,
Year - 2025
DOI:
https://doi.org/10.71431/IJRPAS.2025.4312
View HTML
View PDF
Please allow Pop-Up for this website to view PDF file.
ABSTRACT:
Anti-arthritic activity of Cissus quadrangularis was studied by two methods 1.Inhibition of Albumin denaturation. 2.Human red blood cell membrane (HRBC) stabilization. Egg white denaturation is a process where egg whites experience auxiliary alter and lose their ordinary work due to provocative response, the discharge of incendiary go-betweens disturbs its sensitive structure and hindrance of egg whites denaturation appears the anti-inflammatory action of Cissus quadrangularis . Human red blood cell membrane crack and discharges hemoglobin due to hypotonic condition which is due to incendiary response and stabilization of the layer appears the anti-inflammatory action of the Cissus quadrangularis . As the concentration of the denatured egg whites protein and concentration of film lysis increments the absorbance esteem increments; denaturation of egg whites protein and layer lysis is due to provocative response and discharge of provocative go-betweens. After expansion of the Cissus quadrangularis stem extricate to the test at that point the absorbance esteem diminishes because of the anti-inflammatory movement of the extricate which decreases the egg whites denaturation and membrane lysis.[4,5,6]
Cite this article:
Dr. Sundhararajan R, A. Dhanalakshmi, Latha. S, Lokesh. S, Manibharathi. K, Megala. S, Mohamed Adhil. A. Evaluation of In-vitro Anti-arthritic activity in Methanol and Acetone Extract of Stem of Cissus quadrangularis. IJRPAS, March 2025; 4 (3): 89-94.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4312
01. A Review on Cissus quadrangularis by Ayesha Siddiqua and Sirisha Mittapally
02. Cissus quadrangularis : A Medicinal plant with diverse pharmacological activity by Mahek Sharan, Shivsngi Pandey, Dr. Yamini Dixit.
03. In vitro Anti-arthritic activity of Cissus quadrangularis stem extract by Vaijayanthimala p, Sakthipriya M, Sangameswaran B.
04. Mizushima, Y and Kobayashi, M. Interaction of anti-inflammatory drugs with serum proteins, especially with some biologically active proteins. J Pharma Pharmacol 1968; 20:169-173.
05. Sakat, S, Juvekar AR, Gambhire MN. In vitro antioxidant and anti-inflammatory activity of methanol extract of Oxalis corniculata Linn. International Journal of Pharma and Pharmacological Sciences 2010; 2(1):146-155.
06. Kumar V, Bhat ZA, Kumar D, Bohra P, Sheela S. In vitro anti-inflammatory activity of stem extract of Cissus quadrangularis of Basella alba linn. var. alba. Int J Drug Dev Res 2011; 3(2): 176-9