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Author(s): Shaikh Wahed*1, Shaikh Ujer Rafik2

Email(s): 1shaikhwahedshaikhjaved@gmail.com

Address:

    JIIU's Ali Allana College of Pharmacy, Akkalkuwa, Dist: Nandurbar.

Published In:   Volume - 4,      Issue - 4,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.44056  

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ABSTRACT:
Miliusa tomentosa, a medicinal plant belonging to the Annonaceae family, has been widely studied for its pharmacological potential. This review highlights its taxonomy, phytochemical constituents, pharmacological activities, and medicinal applications. The plant contains a diverse range of bioactive compounds, including alkaloids, flavonoids, lignans, terpenoids, and phenolics, which contribute to its numerous therapeutic properties. M. tomentosa exhibits significant pharmacological activities such as antioxidant, anti-inflammatory, anticancer, antimicrobial, antimalarial, and cardioprotective effects. Notably, its cytotoxic and anticancer properties have been attributed to the presence of geranylated homogentisic acids and acetogenins. The plant is traditionally used for treating respiratory ailments, bacterial infections, and inflammation, while its essential oils have been explored for their antibacterial and analgesic properties. Given its rich phytochemical profile and therapeutic benefits, further research is needed to isolate and characterize its active constituents and validate its traditional uses through clinical studies, enhancing its potential for modern pharmaceutical applications.

Cite this article:
Shaikh Wahed, Shaikh Ujer Rafik. Miliusa tomentosa: a comprehensive review. IJRPAS, April 2025; 4 (4): 66-73.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.44056


Suma K, Nagesh Babu R, Niranjana P, Devaraja S. Purification and characterization of bioactive compounds extracted from (Hoom) Miliusa tomentosa. 2024;13(3):1-3.

2.      Thuy BTP, Van Campenhout S, Dejaegher B, Vander Heyden Y, Nguyen MT, Bui HT, et al. Genus Miliusa: A review of phytochemistry and pharmacology [Internet]. 2019 Aug 14 [cited 2025 Apr 28]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710790/

3.      Sukhadiya M, Dholariya CA, Behera LK, Nayak D, Mehta AA, Sondarva RL. Miliusa tomentosa: A lesser known tree species. 2019 Jul;6(7):1-2.

4.      Indian Institute of Science. Miliusa tomentosa (Roxb.) J. Sinclair [Internet]. Available from: https://indiaflora-ces.iisc.ac.in/FloraPeninsular/herbsheet.php?id=685&cat=7

5.      Global Biodiversity Information Facility. Miliusa tomentosa (Roxb.) J. Sinclair [Internet]. Available from: https://gbit.org/species/3156624

6.      Efloraofindia. Miliusa tomentosa (Roxb.) J. Sinclair [Internet]. 2011 Mar 13 [cited 2025 Apr 28]. Available from: https://efloraofindia.com/2011/03/13/miliusa-tomentosa/

7.      Khedkar D. Miliusa tomentosa (Roxb.) J. Sinclair2 [Internet]. 2019 [cited 2025 Apr 28]. Available from: https://dineshkhedkar.co.in/mpdb/record.php?act=view&id=MT002

8.      NEIST India. Online Structural and Analytics based Database for Herbs of India, Details of Miliusa tomentosa [Internet]. Available from:

 https://neist.res.in/osadhi/detail.php?name=Miliusa+tomentosa

9.      Rahman S, Sultana R, Ismail TS, Islam MS, Rahman R. Saccopetalum tomentosum: Review of its botany, medicinal uses, pharmacological activities and phytochemistry [Internet]. Available from: https://jddtonline.info/index.php/jddt/article/view/5929/5529

 

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