Abstract View

Author(s): Vishakha Tyagi11, Yashvardhan Vats12, Qurratul Ain13, Vipin Kumar14, Shabnam Ain1* Raj Kumar Garg2 and Sneha Pandey15

Email(s): 1shabnam.ain@sanskar.org

Address:

    1Sanskar College of Pharmacy and Research, Ghaziabad, U.P, India 2 K. D. Medical College, Mathura, U.P, India

Published In:   Volume - 4,      Issue - 5,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4504  

 View HTML        View PDF

Please allow Pop-Up for this website to view PDF file.

ABSTRACT:
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder marked by progressive cognitive decline, memory impairment, and behavioural disturbances. Despite extensive research efforts, current therapeutic options remain limited, and there is a pressing need for novel interventions that can slow or halt disease progression. Recently, attention has turned towards natural compounds with potential neuroprotective effects. Fenugreek (Trigonella foenum-graecum) and black cumin (Nigella sativa) are two such herbs that have been historically used in traditional medicine for a variety of health conditions. This review examines the current scientific literature on the neuroprotective potential of Fenugreek and Nigella sativa, focusing on their anti-inflammatory, antioxidant, and neurogenic properties in the context of Alzheimer’s disease. The review also explores the possibility of these herbs being incorporated into integrative therapeutic strategies for AD, alongside conventional treatments, and highlights areas for future research.

Cite this article:
Vishakha Tyagi, Yashvardhan Vats, Qurratul Ain, Vipin Kumar, Shabnam Ain,Raj Kumar Garg and Sneha Pandey.Neuroprotective Potential of Fenugreek and Black Cumin in Alzheimer’s Disease: A Comprehensive Review. IJRPAS, May 2025; 4 (5): 36-45.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4504


1.      Garg, Tarun Gupta, Ankur Bala, Rajni, Sharma, Poonam. (2013). Development and evaluation of herbal deodorant formulations. Journal of Cosmetic Science, 64(4), 351–360.

2.       Pankaj Sharma & Anjali Thakur (2017). Herbal cosmetics: A safe alternative to synthetic deodorants. Journal of Ayurveda and Integrative Medicine, 8(3), 187–194.

3.      Rani, Sunita, Meena, Kapil, Bhardwaj, Ritika, & Soni, Sanjay. (2018). Formulation and evaluation of a herbal deodorant stick using natural essential oils. International Journal of Pharmaceutical Sciences and Research, 9(5), 1894–1899.

4.      Umesh Kumar, Saraogi, Ruchi Pandey, Arvind. (2012). Natural antioxidants in cosmetics: Current trends and future perspectives. Journal of Medicinal Plants Research, 6(25), 4412–4426.

5.       Neha Chauhan, Nitin  Kaushik, Parul, & Yadav Harsh. (2020). Herbal cosmetics: A review on formulations and evaluation. Journal of Cosmetic Dermatology, 19(2), 343–350.

6.       Swati Saini, Vikas Bansal, Sunita Kumar, Anil Agarwal (2015). Antimicrobial and deodorizing properties of essential oils in herbal deodorant formulations. International Journal of Cosmetic Science, 37(5), 467–473.

7.      Dinesh, Deepak Verma, Ritu Patel, Rakesh Saxena, Shraddha. (2016). Evaluation of herbal formulations as natural deodorants. Indian Journal of Pharmaceutical Education and Research, 50(3), 503–509.

8.      Vikram Srivastava, Neelam Tiwari, Anamika Mishra, Ramesh Kumar (2018). Essential oils as a natural alternative for deodorant formulations: A review. Journal of Essential Oil Research, 30 (1), 1–15.

9.      Shalini Singh, Priya Jain (2014). Development of herbal deodorant with antimicrobial properties. Asian Journal of Pharmaceutical Research and Development, 2(2), 98–103.

10.  Saurabh Mishra, Sangeeta Kumari (2021). Sustainable and eco-friendly herbal deodorant formulation: Development and evaluation. International Journal of Green Pharmacy, 15(1), 25–32

11.  Sneha Pandey, Vipin Kumar, Shabnam Ain, Qurratul Ain, Babita Kumar, Nidhi Ruhela, Bhuvnesh. (2025). Alzheimer’s disease: An Overview. International Journal of Research in Pharmacy and Allied Science, 4(2), 13-32.

12.  Sneha Pandey, Vipin Kumar, Shabnam Ain, Qurratul Ain, Bhuvnesh, Nidhi Ruhela, Chhavi Nagar, Babita Kumar. (2025). Impact of Heavy Metals on Respiratory Disease. International Journal of Research in Pharmacy and Allied Science, 4(3), 1-12.

13.  Mehtab Ali, Shabnam Ain, Babita Kumar, Qurratul Ain. (2022). Development and evaluation of eugenol-based gel formulation for analgesic and anti-inflammatory action. Annals of Phytomedicine, 11(1): 338-345.

14.  Parvesh Kumar Dhama, Shabnam Ain, Babita Kumar, Qurratul Ain. (2022). Development and evaluation of topical ointment formulation containing gallic acid as an active pharmaceutical ingredient against bacterial infection and oxidative damage. Annals of Phytomedicine, 11(11): 439-449.

15.  Shabnam Ain, Gaurav Mishra, Babita Kumar, Qurratul Ain, Raj Kumar Garg. (2022). Antidiabetic Potential of Developed Solid Lipid Nanoparticles Loaded with Quercetin: in-vitro and in-silico Studies. Annals of Phytomedicine, 11(2): 1-11.

16.  Zulekha Ali, Shabnam Ain, Shalini Sharma, Qurratul Ain, Babita Kumar. (2025). Recent Advances in Osteoarthritis: Pathophysiology, Diagnosis, and Therapeutic Strategies. Cuestiones de Fisioterapia, 54 (2), 787-811

Related Images:



Recent Images



Gas Chromatographic Profiling and Characterization of Essential Oils from Ocimum tenuiflorum
Artabotrys hexapetalus (I.F) Bhandari: A Phytoconstituent And Pharmacological Review
Fava beans: An Ancient Tool to Manage Parkinson’s Disease
Impact of AI on Pharmacovigilance: A Systematic Review
Neuroprotective Potential of Fenugreek and Black Cumin in Alzheimer’s Disease: A Comprehensive Review
In Silico Studies of Novel BCL-2 and MCL-1 Inhibitors Using Computational Drug Design Tools
Formulation and Evaluation of Soap by using Goat Milk and other Herbals
Formulation and Evaluation of Transdermal Patches Containing Metformin for the Management of Gestational Diabetes
Formulation and evaluation of polyherbal cough syrup
Formulation and Evaluation of a Polyherbal Anti-Dandruff Shampoo Using Traditional Medicinal Plants

Tags


Recomonded Articles:

Author(s): Bhagyashri C. Patel; Sandhya R. Chavhan; H.P. Suryawanshi; R. A. Ahirrao

DOI:         Access: Open Access Read More

Author(s): Harshadeep Seal; Namrata Koushik

DOI:         Access: Open Access Read More

Author(s): Shah Kaunen; Pathan Ahemad; Shah Sahil; Khatik Ali; Abdul Kashif; Abu Asim Azmi

DOI:         Access: Open Access Read More

Author(s): Soni Rishita1*, Salunke Khushi1, Patel Harsh1, Patel Aastha1, Taufik Mulla2, Ambika Nand Jha3

DOI:         Access: Open Access Read More

Author(s): Mehul P. Bagde; Mukesh Rajpurohit; Lalit Chaudhary

DOI:         Access: Closed Access Read More

Author(s): Mohammad Zaid*; Prof. Imran Kalam; Dr. Quazi Majaz

DOI:         Access: Open Access Read More

Author(s): Ansari Owais Ahmad; Pradeep Kumar Mohanty; Pradeep Kumar Yadav

DOI:         Access: Open Access Read More

Author(s): Jayesh M. Rajput

DOI:         Access: Open Access Read More

Author(s): Sneha Pandey; Vipin Kumar; Shabnam Ain*; Qurratul Ain; Bhuvnesh; Nidhi Ruhela Chhavi Nagar and Babita Kumar

DOI: https://doi.org/10.71431/IJRPAS.2025.4301         Access: Open Access Read More

Author(s): Shaikh Shoeb; Mohammad Huzaifa; Bagwan Saman

DOI:         Access: Open Access Read More

Author(s): Museb shaikh Mukhtar; Khalifa Mahmadasif Y; Pathan Ayyaj Magbul; Shaikh Faisal; Shaikh Aman; MD Moiz, Shaikh Arbaj.

DOI:         Access: Open Access Read More

Author(s): Mohammad Aabid, Mohd Zaid Abdul Kaleem, Momin Fatema Zohra Mohd Ateequr Rehman

DOI:         Access: Open Access Read More

Author(s): Bagwan Shahid; Abdul Basit; Khorajia Mohammad; Shah Adnan Wasi; Ansari Arqam

DOI:         Access: Open Access Read More

Author(s): Sneha Pandey; Vipin Kumar; Shabnam Ain*; Qurratul Ain; Babita Kumar; Nidhi Ruhela; Bhuvnesh

DOI: https://doi.org/10.71431/IJRPAS.2025.4202         Access: Open Access Read More

Author(s): Patel Azba Siddiq*; Jain Samiksha Kirtikumar; Patel Samiya Mustak Ali

DOI: https://doi.org/10.71431/IJRPAS.2025.4210         Access: Open Access Read More

Author(s): Mudigonda Sowjanya*; Nishad, Fariya; Malla Rajeshwari; Dr. K. Lakshmi Surekha

DOI:         Access: Open Access Read More

Author(s): Kazi Kaif Aarefoddin; Mohommad Altamash*; Abdullah Danish

DOI: https://doi.org/10.71431/IJRPAS.2025.4313         Access: Open Access Read More

Author(s): Rashmi Rajeghorpade1*; Varsha Shende2 ; Vinod Pawar2; Sohan Patel1; Satyajit Sahoo1

DOI:         Access: Open Access Read More

Author(s): Lokesh. P. Joshi; Devidas. Y. karande; R.N. Chaudhari

DOI:         Access: Open Access Read More

Author(s): Ankit Yadav; Neeraj kumar; Abhishek Kumar; Chetan; Ajay kumar Garg.

DOI:         Access: Open Access Read More