Abstract View

Author(s): Shaikh Samrin Mohammad Tufail*1, Kashtriya Jayshri Prakash2, Kazi Shifa Abdul Wadood.3

Email(s): 1samrinshaikh51221@gmail.com

Address:

    JIIU’s Ali- Allana College Pharmacy, Akkalkuwa, District Nandurbar, MS, India

Published In:   Volume - 4,      Issue - 5,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4514  

 View HTML        View PDF

Please allow Pop-Up for this website to view PDF file.

ABSTRACT:
A significant portion of active compounds in herbal medicines shows strong bioactivity in vitro, but much lower effectiveness in vivo due to their poor lipid solubility and unsuitable molecular size. These factors lead to limited absorption and low bioavailability of the active ingredients from herbal extracts. Herbosome technology helps overcome this challenge by improving the bioavailability of herbal extracts. Acting as a link between conventional and advanced drug delivery systems, herbosomes are complexes formed by natural active ingredients and phospholipids (such as phosphatidylcholine and phosphatidylserine), which enhance the absorption of herbal compounds. This innovative technique is emerging as a valuable approach in phytopharmaceuticals to boost the medicinal potential of herbal extracts. The article provides an overview of herbosome technology, its recent developments, applications for standardized herbal extracts, and offers comprehensive scientific insights and characterization of herbosomes as a promising drug delivery system.

Cite this article:
Shaikh Samrin Mohammad Tufail*, Kashtriya Jayshri Prakash, Kazi Shifa Abdul Wadood. Formulation and Characterization of Herbosome: A Review . IJRPAS, May 2025; 4 (5): 167-173.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4514


1.      Santos AC, Veiga F, Ribeiro AJ. Applications of novel drug delivery System for herbal formulations. Fitoterapia. 2010; 81:680.

2.      Manach C, Scalbert A, Morand C, Remesy C, Jimenez L. Polyphenols: Food sources and bioavailability. Am J Clin Nutr. 2004; 79:727-47.

3.      Bombardelli E, Curri SB, Della Loggia R, Del Negro P, Tubaro A et al. Complex between phospholipids and vegetal derivatives of biological Interest. Fitoterapia 1989; 60:1-9.

4.      Mauri PL, Simonetti P, Gardana C, Minoggio M, Morazzoni P, Bombardelli E et al. Liquid chromatography atmospheric pressure Chemical ionization mass spectrometry of terpene lactones in plasma of Volunteers dosed with Ginkgo biloba L. extracts. Rapid Commun Mass Spectrom. 2001; 15:929 34.

5.      Tawheed A, Bhat SV. A review on phytosome technology as a novel Approach to improve the bioavailability of nutraceuticals. Int J Adv Res Techno. 2012; 43-57.

6.      Sharma S, Tripathi P. Role of traditional herbal medicine in eczema: A Review. Pharmacogn Rev. 2014; 8(16):94-101. Doi:10.4103/0973-7847134229

7.      Alam M, Tripathi J, Khan M, et al. Pharmacological activities of Berberis Aristata – A review. J Appl Pharm Sci. 2012; 2(6):24-31.

8.      Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the Past with a bright future (Review). Mol Med Rep. 2010; 3(6):895-901.Doi:10.3892/mmr.2010.377

 

9.      U Citernesi, M Sciacchitano. Phospholipids active ingredient Complexes. Cosm Toil 1995;110:57-68.

10.  Ravi GS, Chandur V, Shabaraya ARK. Phytosomes: an advanced Herbal drug delivery system. IJPRBS 2015;4:415-32.

11.  Bombardelli E, Mustich G. Bilobalide phospholipid complex, Their uses and formulation containing them, U. S. Patent; 1991.

12.  Valenzuela A, Aspillaga M, Guerra R. Selectivity of silamarin on The increase of glutathione containing in different tissues of Rat. Plant Med 1989;55:42.

13.  Maiti K, Kakali M, Arunava G, Bishnu PS, Pulok KM. Curcumine Phospholipid complex: Preparation,therapeutic evaluation and Pharmacokinetic study in rats. Int J Pharm 2007;330:155-63.

14.  Singh RP, Parpani S, Narke R, Chavan R. Phytosome: recent Advance research for novel drug delivery system. Asian J Pharm Res Dev 2014;2:15-29.

Related Images:



Recent Images



Analytical Quality by Design (AQbD): A Comprehensive Review with Emphasis on Risk Assessment Approaches
Formulation and Evaluation of Nasal Microspheres
Review on Vitamin C Enriched Citrus maxima (Pomelo)
Regulatory Overview: Clinical Trial Application Process in Europe, USA and India
An In-Vitro Evaluation of Anthelmintic Activity of Malatungaw Leaves (Melasthoma malabthricum Linn.) on Roundworms (Ascaris suum)
Targeting Key Signalling Pathways in Leukemia: A Docking-Based Approach for Drug Discovery
Quality by Design Based Analytical Method Development and Validation of Sitagliptin Phosphate by RP-HPLC
An Appraisal On Diclofenac and Its Undesirable Effects: From Pain Relief to Systemic Damage
Novel Approach In Treatment of Cholangiocarcinoma: A Review
High Performance Thin Layer Chromatography method for estimation of Rosuvastatin Calcium and Teneligliptin Hydrobromide Hydrate from its tablet dosage form

Tags


Recomonded Articles:

Author(s): Shaikh Aminoddin Raisoddin; Shifa Maniya; Sayeeda Begum; Naziya Shaikh.

DOI:         Access: Open Access Read More

Author(s): Girisha Chaudhari;Sofiya Morris; Dr. Ashish Jain

DOI:         Access: Open Access Read More

Author(s): Mohammad Zaid*; Prof. Imran Kalam; Dr. Quazi Majaz

DOI:         Access: Open Access Read More

Author(s): Vaibhav S. Jadhav; Vishwajeet G. Thorat; Priyanka V. Gawali; Dr. Balmukund R. Rathi

DOI:         Access: Open Access Read More

Author(s): Swetha Yoganandan1, Gururaj S Kulkarni1, Padmaa M Paarakh2, Surinder Kaur1, A. Muthukumar3

DOI:         Access: Open Access Read More

Author(s): Apurva Arabhavi; Manisha Mane; Neha Desap Sachin Mali; Akanksha Sawant.

DOI:         Access: Open Access Read More

Author(s): Mansuri Jahid; Rehan Deshmukh; Khan Ramiz.V; Sayyed Anas Ali

DOI:         Access: Open Access Read More

Author(s): Venkatesh; Chaithra N; Parthasarathi K Kulkarni; Siddartha H N; Hanumanthachar Joshi K

DOI:         Access: Open Access Read More

Author(s): Khan Juber

DOI:         Access: Open Access Read More

Author(s): Baburao Mohite; Manisha Mane; Sarika Suryavanshi; Shrirang Kharmate; Pranali Patil; Anand Gadad.

DOI:         Access: Open Access Read More

Author(s): Mansoori Safwan Salim; Prof. Rehan Deshmuhk; Dr. G.J. Khan; Shaikh Amaan; Sayyed Ahamad Sayyed Kaleem; Hamza Iliyas Amliwala

DOI:         Access: Open Access Read More

Author(s): Nikhil Ashok Chaudhari*; Pavan Manrang Chaudhari; Madhuri Machindra Bhutekar; Vaibhav Sunil Borse.

DOI: https://doi.org/10.71431/IJRPAS.2025.4415         Access: Open Access Read More

Author(s): Omkar Dhembare; Ashish Jain; Sofiya Moris

DOI:         Access: Open Access Read More

Author(s): Sayed Anasali Israrali*, Dr. Quazi Majaz Ahamad Aejazuddin, Abuzar Khan, Mansuri Jahid Siraj.

DOI:         Access: Open Access Read More

Author(s): Mohammad Faizan; Ismail Moazzam.

DOI:         Access: Open Access Read More

Author(s): Khan Mohammed Anas; Rehan Deshmukh;Khan Ramiz.V; Mohammad Tauheed

DOI:         Access: Open Access Read More

Author(s): M Sohil M Shabbir; Shaikh Imran Kalam; Aejaz Ahmad; G.J. Khan; Md Moiz; Aman Shaikh

DOI:         Access: Open Access Read More

Author(s): Pallavi Chavan; Kedar Bavaskar; Rutuja Sawant; Dr. Ashish Jain

DOI:         Access: Open Access Read More

Author(s): J.J. Naik

DOI:         Access: Open Access Read More