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Author(s): Rathod Balasaheb*1, Kapdekar Lalit2, Londhe Parth3, Haral Avinash4, Khan Rehan Ahmed5, Ravi Pimple6, Dr. R.D Ingole7

Email(s): 1balasahebrathod2002@gmail.com

Address:

    Department of Pharmaceutics DJPS College of Pharmacy, Pathri Dist. Parbhani Maharashtra 431506

Published In:   Volume - 4,      Issue - 6,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4613  

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ABSTRACT:
The rising prevalence of obesity and respiratory disorders such as chronic cough necessitates the development of multifunctional, natural therapeutics with minimal side effects. Herbal medicines, known for their safety and holistic action, offer a promising alternative to synthetic drugs. This study aimed to formulate and evaluate a polyherbal cough syrup comprising Trigonella foenum-graecum (fenugreek), Cinnamomum zeylanicum (cinnamon), Ocimum sanctum (tulsi), and Mentha piperita (peppermint), with honey serving as a natural sweetener and base. The formulation was designed to provide symptomatic relief from cough and exert secondary anti-obesity effects. The herbal syrup exhibited a reddish-brown color, aromatic odor, and sweet taste. The pH was found to be 6.15, indicating compatibility with oral administration. The specific gravity was 0.0012 g/mL, and viscosity was within the acceptable range for syrups. No signs of instability or phase separation were observed. The presence of bioactive compounds such as cinnamaldehyde and saponins supports the syrup’s potential anti-obesity and antioxidant effects.

Cite this article:
Rathod Balasaheb, Kapdekar Lalit, Londhe Parth, Haral Avinash, Khan Rehan Ahmed, Ravi Pimple, Dr. R.D Ingole. Formulation and Evaluation of A Polyherbal Cough Syrup with Potential Anti-Obesity Effects. IJRPAS, June 2025; 4 (6): 116-123.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4613


1.      Ajay Semalty, Rahul Kumar, Mona Semalty: Anti-hyper-lipidemic and anti-obesity activities of ethanolic extract of Trigonella foenum-graecum (seeds) of Himalayan region in diet induced obese mice, Advances in Biomedicine and Pharmacy Volume 2 (5) 2015.

2.      Mule, G. T., Deshmane, K., Shaikh, Bilal S. S., & Hingane, L. D. (2023). Formulation and in-vitro evaluation of polyherbal cough syrup. International Journal of Research in Pharmacy and Allied Science, 2(6), 127–132. https://idealpublication.in/ijrpas/

3.      C. V. Chandrasekaran, M. A. Vijayalakshmi, K. Prakash, V. S. Bansal, J. Meenakshi, A. Amit Review Article: Herbal Approach for Obesity Management.

4.      Devkar Mohan J, Shaikh Shahrukh S. M., Amol G. Jadhao, Miss. Jayshri Sanap, Prashant A. Patil, Formulation and Evaluation of Herbal Syrup. Asian Journal of Pharmaceutical Research and Development. 2021.

5.      S. Akbari et al., Extraction, characterization and antioxidant activity of fenugreek (Trigonella- Foenum Graecum) seed oil. Materials Science for Energy Technologies 2 (2019), 349–355.

6.      Nur Nasulhah Kasim et al, Extraction and Potential of Cinnamon Essential Oil towards Repellency and Insecticidal Activity. International Journal of Scientific and Research Publications, Volume 4, Issue 7, July 2014 1 ISSN 2250-3153.

7.      Bedse A, Nalawade A, Dhamane S, Kachave R, Wagh V, Tare H, Ghangale G. Formulation and Evaluation of Herbal Remedy for Cough.

8.      Jadhao AG, Sanap MJ, Patil PA. Formulation and evaluation of herbal syrup. Asian Journal of Pharmaceutical Research and Development. 2021 Jun 15;9(3):16-22.

9.      Patil AG, Mirajakar KJ, Savekar PL, Bugaditkattikar CV, Shintre SS. Formulation and evaluation of ginger macerated honey base herbal cough syrup. International Journal of Innovative Science and Research Technology. 2020;5(6):582-8.

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