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Author(s): R. Sundhararajan1, P. T. Sangeetha*2, A. Akash Bernat Singh3, Ammar Jaffar Mohideen4, P. Sumitha5, J. Yugavarshini6

Email(s): 1angeethakanadasan05@gmail.com

Address:

    Mohammed Sathak College of Pharmacy, Chennai, Tamilnadu

Published In:   Volume - 5,      Issue - 2,     Year - 2026

DOI: https://doi.org/10.71431/IJRPAS.2026.5211  

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ABSTRACT:
Fast dissolving oral films (FDOFs) are innovative drug delivery systems designed to disintegrate rapidly in the oral cavity without the need for water,enhancing patient compliance, providing rapid onset of action. Herbal medicines have gained global importance due to their safety, accessibility, and therapeutic potential. Achyranthes aspera (Family: Amaranthaceae), commonly known as Prickly Chaff Flower (Apamarga), is traditionally used in Ayurveda for its anti-inflammatory, antimicrobial, anti-venom, analgesic, and wound healing properties. The present study focuses on the development and evaluation of a monoherbal fast dissolving oral film containing Achyranthes aspera extract using the solvent casting method. The formulation aims to provide rapid disintegration, improved bioavailability, and ease of administration. Various evaluation parameters including physicochemical properties, mechanical strength, disintegration time, drugcontent uniformity, and in-vitro release studies were assessed.

Cite this article:
R. Sundhararajan, P. T. Sangeetha*, A. Akash Bernat Singh, Ammar Jaffar Mohideen, P. Sumitha, J. Yugavarshini. In-Vitro Anti-Inflammatory Screening of Clitoria ternatea Flower and its Relevance to Cognitive Development Vulnerability in Nutritionally Stressed Populations. IJRPAS, February 2026; 5(2): 151-158.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2026.5211


1.  World Health Organization. Snakebite environment: A strategy for prevention and control. Geneva: WHO; 2019.

2.  Warrell DA. Snake bite. Lancet. 2010;375(9708):77–88.

3.  Alam MI, Gomes A. Snake venom neutralization by Indian medicinal plants (Vitex negundo and Emblica officinalis) root extracts. J Ethnopharmacology. 2003;86(1):75–80.

4.  Kumar S, Bhowmik D, Chiranjib, Chandira RM. Medicinal uses and pharmacological properties of Achyranthes aspera: A review. Int J Pharm Sci Rev. Res. 2010;3(1):45–49.

5.  Sharma V, Chaudhary U. An overview on indigenous knowledge of Achyranthes aspera. J Pharmacognosy Phytochemical. 2015;3(5):85–89.

6.  Dixit RP, Puthli SP. Oral strip technology: Overview and future potential. J Control Release. 2009;139(2):94–107.

7.  Arya A, Chandra A, Sharma V, Pathak K. Fast dissolving oral films: An innovative drug delivery system. Int J Chemtech Res. 2010;2(1):576–583.

8.  Harborne JB. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. 3rd ed. Chapman & Hall; 1998.

9.  Trease GE, Evans WC. Pharmacognosy. 16th ed. Elsevier; 2009.

10.  Azwanida NN. A review on extraction methods use in medicinal plants. Int J PharmTech Res. 2015;4(3):196–201.

11.  Kokate CK. Practical Pharmacognosy. 4th ed. Vallabh Prakashan; 1994.

12.  Azwanida NN. A review on extraction methods use in medicinal plants. Med Aromat Plants. 2015; 4:196.

13.  Pandey A, Tripathi S. Concept of standardization, extraction and pre-phytochemical screening strategies. J Pharmacogn Phytochem. 2014;2(5):115-119.

14.  Harborne JB. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. 3rd ed. Chapman & Hall; 1998.

15.  Mors WB, et al. Plant natural products active against snake bite. Phytochemistry. 2000; 55:627-642.

16.  Samy RP, et al. Snakebite management: Ethnopharmacologil approach. J Ethnopharmacol. 2008;115:1-17.

17.  Kumar A, et al. A review on pharmacological and phytochemical properties of Achyranthes aspera. Int J Pharm Sci Rev Res. 2010;3(1):45–52.

18. Sharma V, et al. Traditional and medicinal uses of Achyranthes aspera Linn: A review. Int J Res Pharm Biomed Sci. 2011;2(3):1231–1236.

19.  Singh D, et al. Anti-inflammatory activity of Achyranthes aspera Linn. J Ethnopharmacol. 2009;123(1):123–129.

20.    Dixit RP, Puthli SP. Oral strip technology: Overview and future potential. J Control Release2009;139(2):94-107.

21.    Arya A, Chandra A, Sharma V, Pathak K. Fast dissolving oral films: An innovative drug delivery system and dosage form. Int J ChemTech Res. 2010;2(1):576-583.

22.    Dinge A, Nagarsenker M. Formulation and evaluation of fast dissolving films for delivery of triclosan to the oral cavity. AAPS PharmSciTech. 2008;9(2):349-356.

23.    Cilurzo F, Cupone IE, Minghetti P, Selmin F, Montanari L. Fast dissolving films made of maltodextrins. Eur J Pharm Biopharm. 2008;70(3):895-900.

24.    Srivastav S, Singh P, Mishra G, Jha KK, Khosa RL. Achyranthes aspera  An important medicinal plant: A review. J Nat Prod Plant Resour. 2011;1(1):1-14.

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