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Author(s): Baburao Mohite1, Manisha Mane2, Sarika Suryavanshi3, Shrirang Kharmate4, Pranali Patil5, Anand Gadad.6

Email(s): 1baburaomohite4243@gmail.com

Address:

    1Ashokrao Mane College of Pharmacy, Peth Vadgaon
    416112, (M.S.) India

Published In:   Volume - 3,      Issue - 3,     Year - 2024

DOI: Not Available

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ABSTRACT:
The domain of drug delivery technology is expansive and advancing rapidly. It encompasses a wide array of synthetic nanoparticles and medications, often utilized to target specific areas, particularly in cases where drugs exhibit poor pharmacokinetic characteristics and low solubility. Solid lipid carriers combine the benefits of various intelligent nanocarriers to create colloidal drug carrier systems. Solid Lipid Nanoparticles (SLN) represent a distinctive pharmaceutical delivery carrier system that maintains its solid state at room temperature. This carrier technology enables the therapeutic efficacy of medications from multiple categories to be advanced. SLNs find applications in treating cancer, infectious diseases, diabetes, central nervous system disorders, cardiovascular disorders, cosmeceuticals, and various other conditions. They enable enhanced pharmacokinetics and modified drug release. This article delves into the structural features, drug release principles, impact of formulation variables on SLN properties, techniques for SLN preparation, and characterization methods.

Cite this article:
Baburao Mohite, Manisha Mane, Sarika Suryavanshi, Shrirang Kharmate, Pranali Patil, Anand Gadad. Solid Lipid Nanoparticles for Drug Delivery: A Comprehensive Review. IJRPAS, May-June 2024; 3(3): 111-122


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