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Author(s): Dr. Majid S. Khan*1, Devendra Bagul2, Sakshi Bachhav3, Nishigandha Bagul4, Sumit Birari5, Siddharth Batole6, Dr. Avish Maru7

Email(s): 1mskhanpharmacy@gmail.com

Address:

    Loknete Dr. J. D. Pawar College of Pharmacy, Manur, Kalwan, Nashik, Maharashtra

Published In:   Volume - 4,      Issue - 6,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4609  

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ABSTRACT:
Effervescent tablets containing ajwain and fennel have potential as a novel drug delivery system, offering convenience, efficacy, and palatability. These herbal ingredients possess digestive and carminative properties, making them suitable for treating hyperacidity. Hyperacidity, characterized by excessive stomach acid production (pH 1.5-3.5), can cause burning sensations and lead to conditions like GERD, peptic ulcers, and duodenal ulcers. Antacid formulations, such as those containing magnesium or aluminum hydroxides, can help control acidity. The optimized formulation consisted of Anhydrous citric acid, tartaric acid, Bicarbonate of soda, Washing soda, talc, and other ingredients, which demonstrated a good effervescent reaction and minimized issues with capping and sticking.

Cite this article:
Dr. Majid S. Khan, Devendra Bagul, Sakshi Bachhav, Nishigandha Bagul, Sumit Birari, Siddharth Batole, Dr. Avish Maru. Herbal-Based Fennel-Flavored Effervescent Tablets: A Novel Approach to Natural GI Health. IJRPAS, June 2025; 4 (6): 86-95.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4609


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2.      The United States Pharmacopeia (USP). Effervescent Tablets. USP Convention. 2020.

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5.      Felton, L. A. (2019). Remington: Essentials of Pharmaceutics. 2nd ed. Pharmaceutical Press.

6.      Evans, W. C. (2009). Trease and Evans' Pharmacognosy. 16th ed. Elsevier.

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8.      ASM Handbook, Volume 8: Mechanical Testing and Evaluation. ASM International. 2000.

9.      USP <616> Bulk Density and Tapped Density of Powders. United States Pharmacopeia. 2020.

10.  ASTM D6393-14: Standard Test Method for Bulk Solids Characterization by Carr Indices. ASTM International. 2014

11.  Carr, R. L. (1965). Evaluating flow properties of solids. Chemical Engineering, 72(2), 163-168.

12.  Hausner, H. H. (1967). Friction conditions in a mass of metal powder. International Journal ofPowder Metallurgy, 3(2), 7-13

13.  United States Pharmacopeia (USP) <1217> Tablet Breaking Force. USP Convention. 2020.

14.  USP <1217> Tablet Breaking Force. USP Convention. 2020.

15.  USP <905> Uniformity of Dosage Units. USP Convention. 2020.

16.  USP <1216> Tablet Friability. USP Convention. 2020.

17.  European Pharmacopoeia 10.0, 2.9.35. Effervescent tablets. European Directorate for the Quality of Medicines. 2020.

18.  Spectrophotometry in the UV and Visible Region. International Union of Pure and Applied Chemistry (IUPAC). 2014.

19.  USP <791> pH. USP Convention. 2020.

20.  Indian Pharmacopoeia (IP). Assay of Herbal Granules. Indian Pharmacopoeia Commission. 2018.

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