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Author(s): Sonal Balasaheb Bangar1, Tanmay S. Kamble2, Kiran B. Uppar3, Kshitij S. Shirke4, Namrata S. Naware5, Shreya S. Ambatkar6, Mukesh S. Patil7, Dr. Ashish Jain.8

Email(s): 1sonalbangar510@gmail.com

Address:

    Department of Quality Assurance, Shri.D.D. Vispute College of Pharmacy and Research Center, Devad-Vichumbe, Panvel - 410221, Maharashtra, India.

Published In:   Volume - 2,      Issue - 2,     Year - 2023

DOI: Not Available

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ABSTRACT:
In this review article we are going to see brief historical background about some antiemetic drugs. Here we have also discussed about the analytical methods that can be carried out such as spectroscopy and chromatography. Spectroscopy is a field of research that examines how electromagnetic radiation interacts with matter. Whereas High Performance Liquid chromatography is an analytical method used to separate compounds that are soluble in a particular solvent, antiemetic medications are used to treat nausea and vomiting by inhibiting certain receptors that react to neurotransmitter molecules. The current article consists of a review and literature about the use of the drug Metopimazine as an antiemetic drug along with its analytical features. The selection of the drug Metopimazine can be made based on the literature review and improvements that can be done in available methods. Metopimazine is a phenothiazine drug used to treat nausea and vomiting. In this review article, we have also discussed. The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines required for forced degradation studies. A vast literature survey and study we were conclude that not enough work done on Metopimazine in the field of analysis, and there should be improvements in the available methods were possible.

Cite this article:
Sonal Balasaheb Bangar, Tanmay S. Kamble, Kiran B. Uppar, Kshitij S. Shirke, Namrata S. Naware, Shreya S. Ambatkar, Mukesh S. Patil, Dr. Ashish Jain. A Review on Historical Overview of Antiemetic Drug: Metopimazine. IJRPAS, 2023; 2(2): 99-120.


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